MDB - MELIOIDOSIS DATABASE

  Protein search results for - W0M6Y9

Names and origin
Entry : W0M6Y9 (unreviewed)
Entry name : W0M6Y9_BURPE
Protein names : Bifunctional purine biosynthesis protein PurH
Organism : Burkholderia pseudomallei MSHR511
Organism ID : 1249474
Gene names : purH
ORF names : BBQ_412
History
Date of creation : 2014-03-19
Date of modification : 2014-07-09
Date of sequence modification : 2014-03-19
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; IMP cyclohydrolase activity; phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO identifier : GO:0006189; GO:0003937; GO:0004643
Keywords
Ligand & Biological process : Hydrolase; Multifunctional enzyme; Purine biosynthesis; Transferase
General annotation
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.
Sequence similarities : Belongs to PurH family
Protein sequence
Length : 557 residues
>W0M6Y9|W0M6Y9_BURPE Burkholderia pseudomallei MSHR511
MIKQALISVSDKTGIVDFAKALSALGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLD
GRVKTLHPKVHGGILARRDLPEHMQALEAHGIPTIDLLVVNLYPFVQTIAKDDCTLADAI
ENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNTLGYKTNFRLATKVFAHT
AQYDGAITNYLTSLGDDLQHGSRSAYPATLNLAFDKVQDLRYGENPHQSAAFYRDVATPA
GALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGADAGEAYAK
AFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSDAAKQVFAAKQNVRLLEI
ALGEGHNAFDLKRVGGGLLVQSLDSKNVQPRELRVVTKRHPTPKEMDDLLFAWRVAKYVK
SNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVV
VAAGATCVIQPGGSVRDDEVIAAADEHNIAMVVTGVRHFRH