MDB - MELIOIDOSIS DATABASE

  Protein search results for - Q63WH0

Names and origin
Entry : Q63WH0 (reviewed)
Entry name : ISPH1_BURPS
Protein names : 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 (EC 1.17.1.2)
Organism : Burkholderia pseudomallei K96243
Organism ID : 272560
Gene names : ispH1
ORF names : lytB
EC number : 1.17.1.2
History
Date of creation : 2005-07-19
Date of modification : 2014-05-14
Date of sequence modification : 2004-10-25
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 3 iron, 4 sulfur cluster binding; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; dimethylallyl diphosphate biosynthetic process; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process
GO identifier : GO:0051538; GO:0051745; GO:0050992; GO:0019288; GO:0046872; GO:0016114
Keywords
Ligand & Biological process : 3Fe-4S; Complete proteome; Iron; Iron-sulfur; Isoprene biosynthesis; Metal-binding; NADP; Oxidoreductase; Reference proteome
General annotation
Pathway : Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.
Sequence similarities : Belongs to IspH family
Reference
PubMed ID : 15377794
Protein sequence
Length : 350 residues
>Q63WH0|ISPH1_BURPS Burkholderia pseudomallei K96243
MSSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYV
VEDLKKKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVE
VAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVRRLELPDPERVALVTQTT
LSVDDAAEIIGALKAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
SRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVT
NVRALEGIEENVSFPLPRGLNLSSAA