MDB - MELIOIDOSIS DATABASE

  Protein search results for - Q63QX8

Names and origin
Entry : Q63QX8 (reviewed)
Entry name : PUR9_BURPS
Protein names : Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]
Organism : Burkholderia pseudomallei K96243
Organism ID : 272560
Gene names : purH
ORF names : BPSL2896
EC number : 2.1.2.3; 3.5.4.10
History
Date of creation : 2008-01-15
Date of modification : 2014-05-14
Date of sequence modification : 2004-10-25
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; IMP cyclohydrolase activity; phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO identifier : GO:0006189; GO:0003937; GO:0004643
Keywords
Ligand & Biological process : Complete proteome; Hydrolase; Multifunctional enzyme; Purine biosynthesis; Reference proteome; Transferase
General annotation
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.
Sequence similarities : Belongs to PurH family
Reference
PubMed ID : 15377794
Protein sequence
Length : 557 residues
>Q63QX8|PUR9_BURPS Burkholderia pseudomallei K96243
MIKQALISVSDKTGIVDFAKALSALGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLD
GRVKTLHPKVHGGILARRDLPEHMQALEAHGIPTIDLLVVNLYPFVQTIAKDDCTLADAI
ENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNTLGYKTNFRLATKVFAHT
AQYDGAITNYLTSLGDDLQHGSRSAYPATLNLAFDKVQDLRYGENPHQSAAFYRDVATPA
GALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGADAGEAYAK
AFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSDAAKQVFVAKQNVRLLEI
ALGEGHNAFDLKRVGGGLLVQSLDSKNVQPRELRVVTKRHPTPKEMDDLLFAWRVAKYVK
SNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVV
VAAGATCVIQPGGSVRDDEVIAAADEHNIAMVVTGVRHFRH