MDB - MELIOIDOSIS DATABASE

  Protein search results for - M7EFY2

Names and origin
Entry : M7EFY2 (unreviewed)
Entry name : M7EFY2_BURPE
Protein names : Dihydroorotase (DHOase) (EC 3.5.2.3)
Organism : Burkholderia pseudomallei MSHR1043
Organism ID : 1247713
Gene names : pyrC
ORF names : D512_17071
EC number : 3.5.2.3
History
Date of creation : 2013-05-29
Date of modification : 2014-09-03
Date of sequence modification : 2013-05-29
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' UMP biosynthetic process; dihydroorotase activity; pyrimidine nucleobase biosynthetic process; zinc ion binding
GO identifier : GO:0044205; GO:0004151; GO:0019856; GO:0008270
Keywords
Ligand & Biological process : Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc
General annotation
Pathway : Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.
Sequence similarities : Belongs to DHOase family, Type 1 subfamily
Reference
PubMed ID : 23860767
Protein sequence
Length : 376 residues
>M7EFY2|M7EFY2_BURPE Burkholderia pseudomallei MSHR1043
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAY
RERILAAVPAGMTFEPLMTLYLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTD
LLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFIDRVMEPLRRALPGLKVVFEH
ITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGF
ASFFGADFYGLPRSAETVTLRRETWELPREIDAGAGPVVPLRGGEAIGWRLV