MDB - MELIOIDOSIS DATABASE

  Protein search results for - K7Q8W4

Names and origin
Entry : K7Q8W4 (unreviewed)
Entry name : K7Q8W4_BURPE
Protein names : Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)
Organism : Burkholderia pseudomallei BPC006
Organism ID : 1229785
Gene names : purM
ORF names : BPC006_I3349
EC number : 6.3.3.1
History
Date of creation : 2013-02-06
Date of modification : 2014-09-03
Date of sequence modification : 2013-02-06
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; cytoplasm; phosphoribosylformylglycinamidine cyclo-ligase activity
GO identifier : GO:0006189; GO:0005524; GO:0005737; GO:0004641
Keywords
Ligand & Biological process : ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Purine biosynthesis
General annotation
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.
Sequence similarities : Belongs to AIR synthase family
Subcellular location : Cytoplasm.
Reference
PubMed ID : 23144371
Protein sequence
Length : 375 residues
>K7Q8W4|K7Q8W4_BURPE Burkholderia pseudomallei BPC006
MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKK
YREPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKL
DVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGST
IAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLA
LMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWPLPPLFQWLQQHGGVADAEMH
RVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVVV