MDB - MELIOIDOSIS DATABASE

  Protein search results for - K7PUX2

Names and origin
Entry : K7PUX2 (unreviewed)
Entry name : K7PUX2_BURPE
Protein names : Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase)
Organism : Burkholderia pseudomallei BPC006
Organism ID : 1229785
Gene names : purL
ORF names : BPC006_I2385
EC number : 6.3.5.3
History
Date of creation : 2013-02-06
Date of modification : 2014-09-03
Date of sequence modification : 2013-02-06
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; cytoplasm; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity
GO identifier : GO:0006189; GO:0005524; GO:0005737; GO:0006541; GO:0004642
Keywords
Ligand & Biological process : ATP-binding; Complete proteome; Cytoplasm; Glutamine amidotransferase; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis
General annotation
Domains : Glutamine amidotransferase type-1 domain (1)
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.
Sequence similarities : Belongs to FGAMS family
Subcellular location : Cytoplasm.
Reference
PubMed ID : 23144371
Protein sequence
Length : 1451 residues
>K7PUX2|K7PUX2_BURPE Burkholderia pseudomallei BPC006
MAHFSCFPGASALSDFRQTRLLDALKQIDGDIVAVRGQYLHFVNAHEPLTADDEARIGAL
MHYGAPLEPAAEKGATETFVVLPRFGTVSPWASKATDIARHCGLARVRRIERGIEFTVTL
KAGVLGVGAKKALAADARAAVAAALHDRMTESVVASREDARHLFDELPAKPLATVDVLAE
GRAALERANAELGLALADDEIDYLVDAFIKLERNPTDVELMMFAQANSEHCRHKIFNAQW
TIDGQAQDMSLFAMIRNTEKMSPQGTIVAYSDNSSIMSGAHAERWFPRGAGEPGEPGEPG
ERYGRHTELTHTLMKVETHNHPSAISPFPGAATGAGGEIRDEGATGRGARPKAGLTGFTV
SNLDLPGARESWENARDAAQPAAARNAQQPCAPYGRPDRIASPLSIMIDGPLGGAAFNNE
FGRPNLGGYFRVYEQNVGGQVRGYHKPIMIAGGIGNISDAHTHKHDVPAGSLLIQIGGPG
MRIGMGGGAASSMATGANTAELDFDSVQRGNPEIERRAQEVINGCWQLGEHNPILSIHDV
GAGGLSNAFPEIVDGAGKGARFELRKIALEESGLSPREIWSNEAQERYVLAISPADLPRF
EAICARERCPFSVVGVATDERRLQLVDGEATGAAAYPVDMPMEVLLGKPPRMHRDVKRVH
IERAGVDVTGVALADAARDVLRHPTVASKSFLITIGDRTVGGTSVRDQMVGPWQVPVADC
AVTALDYAGFAGEAMTMAERTPLAVIDAPASGRMAVGEAITNIAAAPIASLDKLKLSANW
MAACGTEGEDAKLFDTVKAIGMELCPALGIGIPVGKDSLSMKTKWNDNGVAKEVVAPVSL
IISAFAPVEDVRRHLTPQLRRVADVGASVLIAIDLGRGKNRLGGSILAQVTQQVGDATPD
VDDPEDLKRFFAAVQSLNARDLLLAYHDRSDGGLWATVCEMAFAGHAGVSLNVDMLTLDQ
QHESDYGDAKDWAKQTSGRREDRTIRALFSEELGAVVQVRAADRDAVLGALREHGLSACS
HVIGAVNETDAIEVYRDAKKIYEAPRVELQRAWSEVSWRIARLRDNPACADAEYDAILDA
GDPGLSPVLTFDPAEDVAAPFIATGARPRVAILREQGVNSHLETAYAFDRAGFDAHDVHM
SDLLAGRATLADFAGAVACGGFSYGDVLGAGEGWAKTIRFNDKLADMFAAFFARPDTFAL
GICNGCQMMSSLASMIPGAQAWPKFTRNKSEQFEARFSFVEVQSSPSIFFAGMEGSRIPV
AVAHGEGYADFSQQGDQSRVAVAMRYVDHRGDATERYPFNPNGSPAGITSVTTADGRFTV
LMPHMERVHRTVTMSWHPQGWGEASPWLRVFRNARRWIG