MDB - MELIOIDOSIS DATABASE

  Protein search results for - K7PSS7

Names and origin
Entry : K7PSS7 (unreviewed)
Entry name : K7PSS7_BURPE
Protein names : Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase)
Organism : Burkholderia pseudomallei BPC006
Organism ID : 1229785
Gene names : kynU
ORF names : BPC006_I0886
EC number : 3.7.1.3
History
Date of creation : 2013-02-06
Date of modification : 2014-09-03
Date of sequence modification : 2013-02-06
Protein attributes
Protein existence : Evidence at protein level
Gene Ontology (GO)
GO term name : 'de novo' NAD biosynthetic process from tryptophan; L-kynurenine catabolic process; anthranilate metabolic process; cytoplasm; kynureninase activity; pyridoxal phosphate binding; quinolinate biosynthetic process; tryptophan catabolic process
GO identifier : GO:0034354; GO:0097053; GO:0043420; GO:0005737; GO:0030429; GO:0030170; GO:0019805; GO:0006569
Keywords
Ligand & Biological process : Complete proteome; Hydrolase; Pyridine nucleotide biosynthesis; Pyridoxal phosphate
General annotation
Pathway : Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.
Sequence similarities : Belongs to Kynureninase family
Reference
PubMed ID : 23144371
Protein sequence
Length : 444 residues
>K7PSS7|K7PSS7_BURPE Burkholderia pseudomallei BPC006
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGL
IRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRR
VIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGY
MHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVW
VPKRRQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQ
TDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALI
ARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT