MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LVB8

Names and origin
Entry : I2LVB8 (unreviewed)
Entry name : I2LVB8_BURPE
Protein names : Bifunctional purine biosynthesis protein PurH
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : purH
ORF names : BP1258B_0343
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; IMP cyclohydrolase activity; phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO identifier : GO:0006189; GO:0003937; GO:0004643
Keywords
Ligand & Biological process : Hydrolase; Multifunctional enzyme; Purine biosynthesis; Transferase
General annotation
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.
Sequence similarities : Belongs to PurH family
Reference
PubMed ID : 22615773
Protein sequence
Length : 557 residues
>I2LVB8|I2LVB8_BURPE Burkholderia pseudomallei 1258b
MIKQALISVSDKTGIVDFAKALSALGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLD
GRVKTLHPKVHGGILARRDLPEHMQALEAHGIPTIDLLVVNLYPFVQTIAKDDCTLADAI
ENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNTLGYKTNFRLATKVFAHT
AQYDGAITNYLTSLGDDLQHGSRSAYPATLNLAFDKVQDLRYGENPHQSAAFYRDVATPA
GALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGADAGEAYAK
AFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSDAAKQVFVAKQNVRLLEI
ALGEGHNAFDLKRVGGGLLVQSLDSKNVQPRELRVVTKRHPTPKEMDDLLFAWRVAKYVK
SNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVV
VAAGATCVIQPGGSVRDDEVIAAADEHNIAMVVTGVRHFRH