MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LTN6

Names and origin
Entry : I2LTN6 (unreviewed)
Entry name : I2LTN6_BURPE
Protein names : Dihydroorotase (DHOase) (EC 3.5.2.3)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : pyrX
ORF names : pyrC
EC number : 3.5.2.3
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding
GO identifier : GO:0044205; GO:0004151; GO:0008270
Keywords
Ligand & Biological process : Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc
General annotation
Pathway : Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.
Sequence similarities : Belongs to DHOase family, Type 2 subfamily
Reference
PubMed ID : 22615773
Protein sequence
Length : 457 residues
>I2LTN6|I2LTN6_BURPE Burkholderia pseudomallei 1258b
MKIHIKGGTLIDPAAGTQRQADVFVAAGKVAAIGAAPADFNAAKTIDATGLIVAPGFVDL
SARLREPGYEHKATLESEMAAAVAGGVTSLVCPPDTDPVLDEPGLVEMLKFRARNRNQAH
VYPLGALTVGLKGQVITEMVELTEAGCIGFTQANVPVTDTQVLLRALQYASTYGYTVWLR
PLDAFLAKGGVAASGPVASRLGLSGVPVAAETIALHTLFELMRVTGARVHVARLSSAAGV
ALVRAAKAEGLPVTCDVGANHLHLIDVDIGYFDAQFRLDPPLRAERDREAIRAALADGTI
DAICSDHTPVDDDEKLLPFAEATPGATGLELLLSLTVKWAREAGVPLARALAAITSAPAD
VLKLPAGRIGEGAPADLCVFDPNAHWRVEPRALKSQGHNTPFLGYELPARVCATLVAGQV
AFERR