MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LT01

Names and origin
Entry : I2LT01 (unreviewed)
Entry name : I2LT01_BURPE
Protein names : Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (EC 5.4.3.8) (Glutamate-1-semialdehyde aminotransferase)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : hemL
ORF names : BP1258B_0631
EC number : 5.4.3.8
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Evidence at protein level
Gene Ontology (GO)
GO term name : cytoplasm; glutamate-1-semialdehyde 2,1-aminomutase activity; protoporphyrinogen IX biosynthetic process; pyridoxal phosphate binding; transaminase activity
GO identifier : GO:0005737; GO:0042286; GO:0006782; GO:0030170; GO:0008483
Keywords
Ligand & Biological process : Aminotransferase; Cytoplasm; Isomerase; Porphyrin biosynthesis; Pyridoxal phosphate; Transferase
General annotation
Pathway : Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.
Sequence similarities : Belongs to Class-III pyridoxal-phosphate-dependent aminotransferase family, HemL subfamily
Subcellular location : Cytoplasm.
Reference
PubMed ID : 22615773
Protein sequence
Length : 459 residues
>I2LT01|I2LT01_BURPE Burkholderia pseudomallei 1258b
MSNNQTLFERAQRTIPGGVNSPVRAFRSVGGTPRFVARAQGAYFWDADGKRYIDYIGSWG
PMIVGHVHPDVLAAVQRVLADGFSFGAPTEAEIEIAEEICKLVPSIEQVRMVSSGTEATM
SALRLARGFTGRSRIVKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPADVAKHTTVLE
YNNVAALEEAFAAFGGEIAAVIVEPVAGNMNLVRGTPEFLNALRALTAKHGAVLIFDEVM
CGFRVALGGAQQHYGITPDLTCLGKVIGGGMPAAAFGGRGDIMSHLAPLGGVYQAGTLSG
NPVAVAAGLATLRLIQAPGFHDALADKTRRLADGLAAEARAAGVPFSADAIGGMFGLYFT
EQVPASFADVTKSDIERFNRFFHLMLDAGVYFAPSAYEAGFVSSAHDDATLDATLDAARR
AFAALRA