MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LME5

Names and origin
Entry : I2LME5 (unreviewed)
Entry name : I2LME5_BURPE
Protein names : Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : purL
ORF names : BP1258B_1119
EC number : 6.3.5.3
History
Date of creation : 2012-07-11
Date of modification : 2014-09-03
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; cytoplasm; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity
GO identifier : GO:0006189; GO:0005524; GO:0005737; GO:0006541; GO:0004642
Keywords
Ligand & Biological process : ATP-binding; Cytoplasm; Glutamine amidotransferase; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis
General annotation
Domains : Glutamine amidotransferase type-1 domain (1)
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.
Sequence similarities : Belongs to FGAMS family
Subcellular location : Cytoplasm.
Reference
PubMed ID : 22615773
Protein sequence
Length : 1448 residues
>I2LME5|I2LME5_BURPE Burkholderia pseudomallei 1258b
MAHFSCFPGASALSDFRQTRLLDALKQIDGDIVAVRGQYLHFVNAHEPLTADDEARIGAL
MHYGAPLEPAAEKGATETFVVLPRFGTVSPWASKATDIARHCGLARVRRIERGIEFTVTL
KAGVLGVGAKKALAADARAAVAAALHDRMTESVVASREDARHLFDELPAKPLATVDVLAE
GRAALERANAELGLALADDEIDYLVDAFIKLERNPTDVELMMFAQANSEHCRHKIFNAQW
TIDGQAQDMSLFAMIRNTEKMSPQGTIVAYSDNSSIMSGAHAERWFPRGAGEPGEPGERY
GRHTELTHTLMKVETHNHPSAISPFPGAATGAGGEIRDEGATGRGARPKAGLTGFTVSNL
DLPGARESWENARDAAQPAAARNAQQPCAPYGRPDRIASPLSIMIDGPLGGAAFNNEFGR
PNLGGYFRVYEQNVGGQVRGYHKPIMIAGGIGNISDAHTHKHDVPAGSLLIQIGGPGMRI
GMGGGAASSMATGANTAELDFDSVQRGNPEIERRAQEVINGCWQLGEHNPILSIHDVGAG
GLSNAFPEIVDGAGKGARFELRKIALEESGLSPREIWSNEAQERYVLAISPADLPRFEAI
CARERCPFSVVGVATDERRLQLVDGEATGAAAYPVDMPMEVLLGKPPRMHRDVKRVHIER
AGVDVTGVALADAARDVLRHPTVASKSFLITIGDRTVGGTSVRDQMVGPWQVPVADCAVT
ALDYAGFAGEAMTMAERTPLAVIDAPASGRMAVGEAITNIAAAPIASLDKLKLSANWMAA
CGTEGEDAKLFDTVKAIGMELCPALGIGIPVGKDSLSMKTKWNDNGVAKEVVAPVSLIIS
AFAPVEDVRRHLTPQLRRVADVGASVLIAIDLGRGKNRLGGSILAQVTQQVGDATPDVDD
PEDLKRFFAAVQSLNARDLLLAYHDRSDGGLWATVCEMAFAGHAGVSLNVDMLTLDQQHE
SDYGDAKDWAKQTSGRREDRTIRALFSEELGAVVQVRAADRDAVLGALREHGLSACSHVI
GAVNETDAIEVYRDAKKIYEAPRVELQRAWSEVSWRIARLRDNPACADAEYDAILDAGDP
GLSPVLTFDPAEDVAAPFIATGARPRVAILREQGVNSHLETAYAFDRAGFDAHDVHMSDL
LAGRATLADFAGAVACGGFSYGDVLGAGEGWAKTIRFNDKLADMFAAFFARPDTFALGIC
NGCQMMSSLASMIPGAQAWPKFTRNKSEQFEARFSFVEVQSSPSIFFAGMEGSRIPVAVA
HGEGYADFSQQGDQSRVAVAMRYVDHRGDATERYPFNPNGSPAGITSVTTADGRFTVLMP
HMERVHRTVTMSWHPQGWGEASPWLRVFRNARRWIG