MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LLI7

Names and origin
Entry : I2LLI7 (unreviewed)
Entry name : I2LLI7_BURPE
Protein names : 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine synthase) (Methionine synthase, vitamin-B12 independent isozyme)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : metE
ORF names : BP1258A_0608
EC number : 2.1.1.14
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; methionine biosynthetic process; zinc ion binding
GO identifier : GO:0003871; GO:0009086; GO:0008270
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Metal-binding; Methionine biosynthesis; Methyltransferase; Repeat; Transferase; Zinc
General annotation
Pathway : Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.
Sequence similarities : Belongs to Vitamin-B12 independent methionine synthase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 816 residues
>I2LLI7|I2LLI7_BURPE Burkholderia pseudomallei 1258a
MTTAHILGFPRIGAQRELKFALERYWRDGASADAERALVDTGRALRAEHWRIERDAGLDC
VTVGDFAWYDHVLTTLAHVGGLPRRFGFDARALTLADYFAAARGNAAQPAMEMTKWFDTN
YHYLVPEYSPATTFGPGVEWLFDEVREARALGHRAKAALVGPLTLLWLGKARDGLVERLA
LLPRLVPAYRALLARLREAGVDWVQIDEPIFALDLPDAWRDAARPTYEALAPGAPKLLVA
TYFDDASEHAALLKALPVAGLHIDLVRADAQLDAFVADYPADKVLSCGIVDGRNVWRNDL
DRSLARLAPVRDALGERLWVATSCSLLHVPVDLAHEPRLDEELKTWLAFAAQKTREVAAL
RDALVKGRAAVAAEFDDAAAAAAARRTSARIHNPLVKRRVAALTDADARRASAYSVRAAA
QRARFGLPLLPTTTIGSFPQTPEIRRARAAFKQGVLDHLGYLEAMREQVRIAIDKQLAYG
LDVLVHGEAERNDMVEYFGELLWGFAITSNGWVQSYGSRCVKPPLVYGDVYLPEPMTVGW
ASYAQSLSAKPVKGMLTGPVTMLQWSFVRDDQPRATTALQIALALRQETLDLEKAGIGMI
QIDEPALREGLPLKARERAAYLDWAVRAFGIAASGVADDTQIHTHMCYSEFGDILPSIAA
LDADVISIETTRSNMELLDAFETFDYPNEIGPGVYDIHSPRVPDADEIERLILLALERIP
AQRLWVNPDCGLKTREWRQVDAALAAMVDAAKRVRQKVEEAAPA