MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LHG4

Names and origin
Entry : I2LHG4 (unreviewed)
Entry name : I2LHG4_BURPE
Protein names : Homoserine dehydrogenase (EC 1.1.1.3)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : hom
ORF names : BP1258A_1085
EC number : 1.1.1.3
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : NADP binding; amino acid binding; homoserine dehydrogenase activity; isoleucine biosynthetic process; methionine biosynthetic process; threonine biosynthetic process
GO identifier : GO:0050661; GO:0016597; GO:0004412; GO:0009097; GO:0009086; GO:0009088
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Isoleucine biosynthesis; Methionine biosynthesis; NADP; Oxidoreductase; Threonine biosynthesis
General annotation
Pathway : Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3. Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.
Sequence similarities : Belongs to Homoserine dehydrogenase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 474 residues
>I2LHG4|I2LHG4_BURPE Burkholderia pseudomallei 1258a
MEPIKVGLLGFGTVGGGTFKVLRRNQEEIKRRAGRGIEIARVAVRNPAKALAALDGDANG
VSIGDDFNAVVDDPSIAIVAEMIGGTGLARELVLRAIANGKHVVTANKALLAVHGTEIFE
AARAKGVMVAFEAAVAGGIPIIKALREGLTANRIQYIAGIINGTTNYILSEMRERGLDFA
TALKAAQELGYAEADPTFDIEGVDAAHKATIMSAIAFGVPVQFDRAYVEGISRLAATDIK
YAEELGYRIKLLGITRRTERGIELRVHPTLIPAKRLLANVEGAMNAVVVHGDAVGTTLYY
GKGAGAEPTASAVVADLVDVTRLHTADPEHRVPHLAFQPDSLSNTPILPIEEVTSGYYLR
LRVADQTGVLADITRILAESGISIDALLQKESEQVDDANGETDIILITHETVEKNVNAAI
ARIESLATVVSKVTKLRMEALN