MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LEX3

Names and origin
Entry : I2LEX3 (unreviewed)
Entry name : I2LEX3_BURPE
Protein names : Phosphomethylpyrimidine synthase (EC 4.1.99.17) (Hydroxymethylpyrimidine phosphate synthase) (Thiamine biosynthesis protein ThiC)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : thiC
ORF names : BP1258B_1954
EC number : 4.1.99.17
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 4 iron, 4 sulfur cluster binding; lyase activity; thiamine biosynthetic process; thiamine diphosphate biosynthetic process; zinc ion binding
GO identifier : GO:0051539; GO:0016829; GO:0009228; GO:0009229; GO:0008270
Keywords
Ligand & Biological process : 4Fe-4S; Iron; Iron-sulfur; Lyase; Metal-binding; S-adenosyl-L-methionine; Thiamine biosynthesis; Zinc
General annotation
Pathway : Cofactor biosynthesis; thiamine diphosphate biosynthesis.
Sequence similarities : Belongs to ThiC family
Reference
PubMed ID : 22615773
Protein sequence
Length : 687 residues
>I2LEX3|I2LEX3_BURPE Burkholderia pseudomallei 1258b
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPP
IYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAEL
RFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAK
LAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRN
FLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPI
GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGI
VSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG
ELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAP
GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHP
GAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM
KITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ