MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LCF8

Names and origin
Entry : I2LCF8 (unreviewed)
Entry name : I2LCF8_BURPE
Protein names : Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : ilvD
ORF names : BP1258B_2264
EC number : 4.2.1.9
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 4 iron, 4 sulfur cluster binding; dihydroxy-acid dehydratase activity; isoleucine biosynthetic process; metal ion binding; valine biosynthetic process
GO identifier : GO:0051539; GO:0004160; GO:0009097; GO:0046872; GO:0009099
Keywords
Ligand & Biological process : 4Fe-4S; Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Iron; Iron-sulfur; Lyase; Metal-binding
General annotation
Pathway : Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4. Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.
Sequence similarities : Belongs to IlvD/Edd family
Reference
PubMed ID : 22615773
Protein sequence
Length : 597 residues
>I2LCF8|I2LCF8_BURPE Burkholderia pseudomallei 1258b
MSYNRRSKNITQGVARSPNRSMYYALGYQKEDFDKPMIGIANGHSTITPCNAGLQRLSDA
AVAAVKDAGANPQIFGTPTISDGMSMGTEGMKYSLVSREVIADCIETCVQGQWMDGVVVV
GGCDKNMPGGMIALARINVPGIYVYGGTIRPGHWKGHDLTIVSSFEAVGEFTAGRMSQED
FEGVEKNACPTTGSCGGMYTANTMSSSFEALGMSLLYSSTMANPDQEKVDSAAESARVLV
EAVKKDLKPRDIITKQSIENAVSVIMATGGSTNAVLHYLAIAHAAEIDWSIEDFERIRKR
VPVICDLKPSGQYVATDLHAAGGIPQVMKLLLDAGLLHGDCMTITGRTLAEELKDVPSVP
RADQKVIHPIDQALYKEGHLAILKGNLAEDGAVAKITGLKNPVITGPARVFDDEQSALAA
ILDDRIRAGDVVVLRYLGPQGGPGMPEMLAPTSAIIGKGLGESVGLITDGRFSGGTWGMV
VGHVAPEAFVGGTIALVQEGDSITIDAHKLLLQLNVDDAELARRRAAWKQPAPRYTRGVL
AKYAALARPANQGAVTG