MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2LAC8

Names and origin
Entry : I2LAC8 (unreviewed)
Entry name : I2LAC8_BURPE
Protein names : Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : hemH
ORF names : purC
EC number : 6.3.2.6
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO identifier : GO:0006189; GO:0005524; GO:0004639
Keywords
Ligand & Biological process : ATP-binding; Ligase; Nucleotide-binding; Purine biosynthesis
General annotation
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
Sequence similarities : Belongs to SAICAR synthetase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 316 residues
>I2LAC8|I2LAC8_BURPE Burkholderia pseudomallei 1258b
MSTLYESTLRSLPLLGRGKVRDNYALGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQM
ANFWFDRLAHIVPNHLTGVAPETVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSG
WKDYQATGKVCGVELPAGLSNAQKLPEPIFTPAAKAEMGHHDENISFEETERRIGTELAA
TIRDISIRLYKEAADYAATRGIIIADTKFEFGLDEHGELFLMDEALTADSSRFWPADEYR
VGTNPPSFDKQFVRDWLEAQNWNKAPPAPKLPDDVVAKTSAKYQEALERITGKTLD