MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2L8E3

Names and origin
Entry : I2L8E3 (unreviewed)
Entry name : I2L8E3_BURPE
Protein names : Ketol-acid reductoisomerase (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacyl reductoisomerase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : ilvC
ORF names : BP1258A_1956
EC number : 1.1.1.86
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : coenzyme binding; isoleucine biosynthetic process; isomerase activity; ketol-acid reductoisomerase activity; valine biosynthetic process
GO identifier : GO:0050662; GO:0009097; GO:0016853; GO:0004455; GO:0009099
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Isomerase; NADP; Oxidoreductase
General annotation
Pathway : Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4. Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.
Sequence similarities : Belongs to Ketol-acid reductoisomerase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 362 residues
>I2L8E3|I2L8E3_BURPE Burkholderia pseudomallei 1258a
MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRRGGASWSKAENAG
LAVKEVAEAVKGADVVMMLLPDEQIAAVYAQEVHANIKEGAALAFAHGFNVHYGQVIPRA
DLDVIMVAPKAPGHTVRGTYAQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIE
TNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYE
GGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAGAPT
LQSRRRLTAEHQIEQVGSKLRAMMPWIAKNKLVDQSKN