MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2L8E0

Names and origin
Entry : I2L8E0 (unreviewed)
Entry name : I2L8E0_BURPE
Protein names : 2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : leuA
ORF names : BP1258A_1953
EC number : 2.3.3.13
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 2-isopropylmalate synthase activity; leucine biosynthetic process
GO identifier : GO:0003852; GO:0009098
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Leucine biosynthesis; Transferase
General annotation
Pathway : Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.
Sequence similarities : Belongs to Alpha-IPM synthase/homocitrate synthase family, LeuA type 1 subfamily
Reference
PubMed ID : 22615773
Protein sequence
Length : 551 residues
>I2L8E0|I2L8E0_BURPE Burkholderia pseudomallei 1258a
MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKQLERMKVDVIEAGFAASSNGDFDAIQT
IASQVKDSTICSLARANDKDIQRAADALKPANSFRIHTFIATSPLHMEKKLRMTPDQVFE
QARLAVRFARKFTDNIEFSPEDGSRSDMDFLCRVLEAVIAEGATTINIADTVGYGVPELY
GNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNT
SLEEIVMAVKTRKDYFGLDLGIDTTQIVPASKLVSQITGFVVQPNKAVVGANAFAHASGI
HQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSEAELNAAFA
RFKDLADRKAEIFDEDIIAIVTEEESALAQEHEHYKFVSLAQRSETGERPQAKVVFAVDG
DEVAGEASGNGPVDATFNAIETEVGSGAELLLYSVNAITTGTQAQGEVTVRLSKSGRIVN
GVGTDPDIVAASAKAYIAALNKLYSNADKLNPQRA