MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2L7Y9

Names and origin
Entry : I2L7Y9 (unreviewed)
Entry name : I2L7Y9_BURPE
Protein names : Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : purD
ORF names : BP1258A_1990
EC number : 6.3.4.13
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; magnesium ion binding; manganese ion binding; phosphoribosylamine-glycine ligase activity; purine nucleobase biosynthetic process
GO identifier : GO:0006189; GO:0005524; GO:0000287; GO:0030145; GO:0004637; GO:0009113
Keywords
Ligand & Biological process : ATP-binding; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Purine biosynthesis
General annotation
Domains : ATP-grasp domain (1)
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.
Sequence similarities : Belongs to GARS family
Reference
PubMed ID : 22615773
Protein sequence
Length : 457 residues
>I2L7Y9|I2L7Y9_BURPE Burkholderia pseudomallei 1258a
MKLLVVGSGGREHALAWKLAQSPRVQLVYVAPGNGGTAQDERLKNVDLSSLDDLADFAES
EGVAFTLVGPEAPLAAGIVNHFRARGLKIFGPTKEAAQLESSKDFAKAFMKRHGIPTADY
ETFTDAAAAHAYLDSKGAPIVVKADGLAAGKGVVVAMTLEEAHAAVDMMLSGNKLGDAGA
RVVIEAFLDGEEASFIVMVDGKHALALASSQDHKRLLDEDRGPNTGGMGAYSPAPIVTPQ
MHARVMREIIMPTVRGMEKDGIRFTGFLYAGLMIDRDGNPRTLEFNCRMGDPETQPIMAR
LKSDFSKVVEQAIAGTLDTVELDWDRRTALGVVLAAHGYPDAPRKGDRINGIPAETAHAV
TFHAGTTFDGDKLVTSGGRVLCVVGLADSVRGAQQAAYETINQINFEGMQYRRDIGYRAL
NRKTV