MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2L6H6

Names and origin
Entry : I2L6H6 (unreviewed)
Entry name : I2L6H6_BURPE
Protein names : Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (Tryptophan pyrrolase) (Tryptophanase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : kynA
ORF names : BP1258A_2221
EC number : 1.13.11.11
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : heme binding; metal ion binding; tryptophan 2,3-dioxygenase activity; tryptophan catabolic process to kynurenine
GO identifier : GO:0020037; GO:0046872; GO:0004833; GO:0019441
Keywords
Ligand & Biological process : Dioxygenase; Heme; Iron; Metal-binding; Oxidoreductase; Tryptophan catabolism
General annotation
Pathway : Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
Sequence similarities : Belongs to Tryptophan 2,3-dioxygenase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 339 residues
>I2L6H6|I2L6H6_BURPE Burkholderia pseudomallei 1258a
METNVNSGHMQPPGDDAAPRCPFAGAHAPDAPHVPEAAGDDAQAGWHRAQLDFSQSMSYG
DYLSLDPILDAQHPRSPDHNEMLFIIQHQTSELWMKLALYELRAALASIRDDALPPAFKM
LARVSRVLEQLVQAWNVLATMTPSEYSAMRPYLGASSGFQSYQYRELEFILGNKNAQMLR
PHAHRPAIHAHLEASLQAPSLYDEVIRLLARRGFPIAAERLDADWTQPTRHDRTVEAAWL
AVYREPNAHWELYEMAEELVDLEDAFRQWRFRHVTTVERIIGFKQGTGGTSGAPYLRKML
DVVLFPELWHVRTTL