MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2L4S7

Names and origin
Entry : I2L4S7 (unreviewed)
Entry name : I2L4S7_BURPE
Protein names : Protoheme IX farnesyltransferase (EC 2.5.1.-) (Heme B farnesyltransferase) (Heme O synthase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : ctaB
ORF names : BP1258A_2455
EC number : 2.5.1.-
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : heme O biosynthetic process; integral component of membrane; plasma membrane; protoheme IX farnesyltransferase activity
GO identifier : GO:0048034; GO:0016021; GO:0005886; GO:0008495
Keywords
Ligand & Biological process : Cell membrane; Heme biosynthesis; Membrane; Transferase; Transmembrane; Transmembrane helix
General annotation
Pathway : Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.
Sequence similarities : Belongs to UbiA prenyltransferase family, Protoheme IX farnesyltransferase subfamily
Subcellular location : Cell membrane; Multi-pass membrane protein.
Reference
PubMed ID : 22615773
Protein sequence
Length : 320 residues
>I2L4S7|I2L4S7_BURPE Burkholderia pseudomallei 1258a
MDTTLSHTPGSRLSQYLALTKPRVTQLAVFCAVIGMFLATPGMVPWKVLLGGTIGIGLLA
GSAFAINCLVEQKIDAMMRRTAWRPSARGEITTLQILAFSTVLGGLGAWTLYTFTNPLTM
WLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIF
VWTPPHFWVLALYRRKDYENAGLPMLPVTHGEQFTRLHILLYTVILFAVTMMPFISGMSG
AVYLTSAVLLGALFLAYAWKIYRDYSDALARRAFRYSIVYLSLLFAALLVDHYARPVIGM