MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2KX80

Names and origin
Entry : I2KX80 (unreviewed)
Entry name : I2KX80_BURPE
Protein names : Macrolide export ATP-binding/permease protein MacB (EC 3.6.3.-)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : macB
ORF names : BP1258A_3455
EC number : 3.6.3.-
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : ATP binding; ATP-binding cassette (ABC) transporter complex; ATPase activity; antibiotic transporter activity; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; response to antibiotic
GO identifier : GO:0005524; GO:0043190; GO:0016887; GO:0042895; GO:0016820; GO:0046677
Keywords
Ligand & Biological process : ATP-binding; Antibiotic resistance; Cell inner membrane; Cell membrane; Hydrolase; Membrane; Nucleotide-binding; Transmembrane; Transmembrane helix; Transport
General annotation
Domains : ABC transporter domain (1)
Sequence similarities : Belongs to ABC transporter superfamily; ABC transporter superfamily, Macrolide exporter (TC 3.A.1.122) family
Subcellular location : Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Reference
PubMed ID : 22615773
Protein sequence
Length : 697 residues
>I2KX80|I2KX80_BURPE Burkholderia pseudomallei 1258a
MTGPLLQLTRVTRRFPAGEKDVVVLDDVSLSIDAGEIVAIVGASGSGKSTLMNILGCLDH
PSSGSYTVGGRETSELESDELARLRREHFGFIFQRYHLLPHLCAAENVEMPAVYAGSAQA
QRRERALALLARLGLSDRASHRPSQLSGGQQQRVSIARALMNGGEVILADEPTGALDSKS
GRDVIRVLRELNALGHTVIIVTHDEQVAAHARRIIEISDGRIVGDRLNPHADAADAAPDA
SGGAQPRRARRLSAGVGRFAEAFRMAWIALVSHRLRTLLTMLGIIIGITSVVSIVAIGEG
AKRYMLDEIGSIGTNTINVYPGADWGDSRADAIQTLVAADAAALADQIYIDSATPETSRS
LLLRYRNVDVNALVSGVGERFFQVRGMKLAQGIAFGADEVRRQAQVAVIDENTRRKLFGA
NPNPLGEVILIDNLPCVVIGVTASKKSAFGDMKNLNVWVPYTTASGRLFGQRHLDSITVR
VRDGQPSDAAERSLTKLMLQRHGRKDFFTYNMDSVVKTVEKTGQSLTLLLSLIAVISLVV
GGIGVMNIMLVSVTERTREIGIRMAVGARQTDIMQQFLVEAVTVCLMGGAIGIVLSFGMS
FVFSLFVDQWKMVFSAASIASAFLCSTLIGVVFGFMPARNASRLDPIDALARD