MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2KNQ7

Names and origin
Entry : I2KNQ7 (unreviewed)
Entry name : I2KNQ7_BURPE
Protein names : 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (Isopropylmalate isomerase)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : leuC
ORF names : BP1258B_4978
EC number : 4.2.1.33
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 3-isopropylmalate dehydratase activity; 4 iron, 4 sulfur cluster binding; isomerase activity; leucine biosynthetic process; metal ion binding
GO identifier : GO:0003861; GO:0051539; GO:0016853; GO:0009098; GO:0046872
Keywords
Ligand & Biological process : 4Fe-4S; Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Iron; Iron-sulfur; Isomerase; Leucine biosynthesis; Lyase; Metal-binding
General annotation
Pathway : Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.
Sequence similarities : Belongs to Aconitase/IPM isomerase family, LeuC type 1 subfamily
Reference
PubMed ID : 22615773
Protein sequence
Length : 501 residues
>I2KNQ7|I2KNQ7_BURPE Burkholderia pseudomallei 1258b
MAQTLYDKLWNSHVVHTEEDGTALLYIDRQLLHEVTSPQAFEGLKLAQRPVWRISANLAV
SDHNVPTTDRSHGIADPVSKLQVDTLDANCDAYGITQFKMNDVRQGIVHIIGPEQGATLP
GMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLQKKSKNMLVKVEGQLPRGCTA
KDIVLAIIGRIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGMVAVDDTTV
EYLKGRPFVPTGAEWDQAVEYWKTFRSDEGAQFDRVVELDAAQIVPQVTWGTSPEMVTSI
DGRVPDPEREKDPVKRDAMERALAYMALAPNTPIEAIKVDKIFIGSCTNARIEDIRAAAY
VVKKLNRRVAPNVRLAMVVPGSGLVKAQAEREGLDKVFTEAGFEWREPGCSMCLAMNADR
LEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAIEGHFVDIRRLG