MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2KNQ2

Names and origin
Entry : I2KNQ2 (unreviewed)
Entry name : I2KNQ2_BURPE
Protein names : Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)
Organism : Burkholderia pseudomallei 1258b
Organism ID : 1086033
Gene names : asd
ORF names : BP1258B_4973
EC number : 1.2.1.11
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' L-methionine biosynthetic process; N-acetyl-gamma-glutamyl-phosphate reductase activity; NAD binding; NADP binding; aspartate-semialdehyde dehydrogenase activity; cytoplasm; diaminopimelate biosynthetic process; isoleucine biosynthetic process; lysine biosynthetic process via diaminopimelate; threonine biosynthetic process
GO identifier : GO:0071266; GO:0003942; GO:0051287; GO:0050661; GO:0004073; GO:0005737; GO:0019877; GO:0009097; GO:0009089; GO:0009088
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Diaminopimelate biosynthesis; Lysine biosynthesis; Methionine biosynthesis; NADP; Oxidoreductase; Threonine biosynthesis
General annotation
Pathway : Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4. Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3. Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.
Sequence similarities : Belongs to Aspartate-semialdehyde dehydrogenase family
Reference
PubMed ID : 22615773
Protein sequence
Length : 401 residues
>I2KNQ2|I2KNQ2_BURPE Burkholderia pseudomallei 1258b
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPSFAKNETTLKDATSID
DLKKCDAIITCQGGDYTSDVFPKLRAAGWNGYWIDAASSLRMKDDAVIILDPVNLNVIKD
ALVNGTKNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELLAQMGA
LNGAVAAQLADPASAILDIDRRVLAAMNGDAMPTSQFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAETNKILGKPAMGEPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGMLA
SANDWVKVVPNEREASMRDLSPAKVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
EPLRRMLRILLDK