MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2KH58

Names and origin
Entry : I2KH58 (unreviewed)
Entry name : I2KH58_BURPE
Protein names : Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : guaB
ORF names : BP1258A_5115
EC number : 1.1.1.205
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : GMP biosynthetic process; IMP dehydrogenase activity; adenyl nucleotide binding; metal ion binding
GO identifier : GO:0006177; GO:0003938; GO:0030554; GO:0046872
Keywords
Ligand & Biological process : CBS domain; GMP biosynthesis; Metal-binding; NAD; Oxidoreductase; Potassium; Purine biosynthesis; Repeat
General annotation
Domains : CBS domains (2)
Pathway : Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
Sequence similarities : Belongs to IMPDH/GMPR family
Reference
PubMed ID : 22615773
Protein sequence
Length : 522 residues
>I2KH58|I2KH58_BURPE Burkholderia pseudomallei 1258a
MRLIQKALTFDDVLLVPAFSDVLPRDTSLKTQLTRNISLNMPLVSAAMDTVTEGRLAIAM
AQQGGVGIVHKNLTPVEQAREVAKVKRFESGVVRDPITVPPSMKVRDVIALSRQHGISGF
PVVEGPKLVGIVTNRDLRFETRLDEPVKSIMTPRERLVTVAEGTPLAEAKALMHSHRLER
VLVVNDAFELRGLMTVKDITKQTEHPEACKDEHGKLRVGAAVGVGADNEERVELLVQAGV
DVIVVDTAHGHSKGVLERVRWVKQNFPKVEVIGGNIATAAAAKALVEYGADAVKVGIGPG
SICTTRIVAGVGVPQISAIANVSDALRGTGVPCVADGGIRFSGDVSKALAAGANAVMMGS
MFAGTEEAPGDVFLYQGRQYKSYRGMGSVGAMKDGAADRYFQDNSANIDKLVPEGIEGRV
AYKGSVNAIIFQLIGGVRASMGYCGCKTIAELHEKAEFVQITAAGMRESHVHDVQITKEA
PNYHVD