MDB - MELIOIDOSIS DATABASE

  Protein search results for - I2KGF6

Names and origin
Entry : I2KGF6 (unreviewed)
Entry name : I2KGF6_BURPE
Protein names : 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase)
Organism : Burkholderia pseudomallei 1258a
Organism ID : 1086032
Gene names : ipk
ORF names : ispE
EC number : 2.7.1.148
History
Date of creation : 2012-07-11
Date of modification : 2014-07-09
Date of sequence modification : 2012-07-11
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity; ATP binding; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; terpenoid biosynthetic process
GO identifier : GO:0050515; GO:0005524; GO:0019288; GO:0016114
Keywords
Ligand & Biological process : ATP-binding; Isoprene biosynthesis; Kinase; Nucleotide-binding; Transferase
General annotation
Pathway : Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.
Sequence similarities : Belongs to GHMP kinase family, IspE subfamily
Reference
PubMed ID : 22615773
Protein sequence
Length : 313 residues
>I2KGF6|I2KGF6_BURPE Burkholderia pseudomallei 1258a
MTDTTRSLRDCLAPAKLNLFLHITGRRPDGYHALQSVFQLLDWGDRLHFTLRDDGKVSRV
TDVPGVPEESDLVVRAASLLKAHAGATLGVDIEIDKRLPMGAGLGGGSSDAATTLLALNR
LWRLDLPRTTLQSLAVKLGADVPFFVFGKNAFAEGIGEALQAVELPARWFLVVTPRVHVP
TAAIFSEKSLTRDSKPITITDFLAQRGIDAGWPDSFGRNDMQPVVTSKYAEVAKVVEWFY
NLTPARMTGSGASVFAAFKSKADAEAAQAKLPAGWNSAVAESMSEHPLFAFAS