MDB - MELIOIDOSIS DATABASE

  Protein search results for - B7CIK8

Names and origin
Entry : B7CIK8 (unreviewed)
Entry name : B7CIK8_BURPE
Protein names : Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase)
Organism : Burkholderia pseudomallei 576
Organism ID : 557724
Gene names : kynU
ORF names : BUC_1100
EC number : 3.7.1.3
History
Date of creation : 2009-02-10
Date of modification : 2014-07-09
Date of sequence modification : 2009-02-10
Protein attributes
Protein existence : Evidence at protein level
Gene Ontology (GO)
GO term name : 'de novo' NAD biosynthetic process from tryptophan; L-kynurenine catabolic process; anthranilate metabolic process; cytoplasm; kynureninase activity; pyridoxal phosphate binding; quinolinate biosynthetic process; tryptophan catabolic process
GO identifier : GO:0034354; GO:0097053; GO:0043420; GO:0005737; GO:0030429; GO:0030170; GO:0019805; GO:0006569
Keywords
Ligand & Biological process : Hydrolase; Pyridine nucleotide biosynthesis; Pyridoxal phosphate
General annotation
Pathway : Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.
Sequence similarities : Belongs to Kynureninase family
Protein sequence
Length : 444 residues
>B7CIK8|B7CIK8_BURPE Burkholderia pseudomallei 576
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGL
IRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRR
VIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGY
MHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVW
VPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQ
TDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALI
ARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT