MDB - MELIOIDOSIS DATABASE

  Protein search results for - A8KWR7

Names and origin
Entry : A8KWR7 (unreviewed)
Entry name : A8KWR7_BURPE
Protein names : Dihydroorotase (DHOase) (EC 3.5.2.3)
Organism : Burkholderia pseudomallei Pasteur 52237
Organism ID : 331978
Gene names : pyrC
ORF names : BURPSPAST_AB0266
EC number : 3.5.2.3
History
Date of creation : 2007-12-04
Date of modification : 2014-06-11
Date of sequence modification : 2007-12-04
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' UMP biosynthetic process; dihydroorotase activity; zinc ion binding
GO identifier : GO:0044205; GO:0004151; GO:0008270
Keywords
Ligand & Biological process : Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc
General annotation
Pathway : Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.
Sequence similarities : Belongs to DHOase family, Type 2 subfamily
Protein sequence
Length : 457 residues
>A8KWR7|A8KWR7_BURPE Burkholderia pseudomallei Pasteur 52237
MKIHIKGGTLIDPAAGTQRQADVFVAAGKVAAIGAAPADFNAAKTIDATGLIVAPGFVDL
SARLREPGYEHKATLESEMAAAVAGGVTSLVCPPDTDPVLDEPGLVEMLKFRARNRNQAH
VYPLGALTVGLKGQVITEMVELTEAGCIGFTQANVPVTDTQVLLRALQYASTYGYTVWLR
PLDAFLAKGGVAASGPVASRLGLSGVPVAAETIALHTLFELMRVTGARVHVARLSSAAGV
ALVRAAKAEGLPVTCDVGANHLHLIDVDIGYFDAQFRLDPPLRAERDREAIRAALADGTI
DAICSDHTPVDDDEKLLPFAEATPGATGLELLLSLTVKWAREAGVPLARALAAITSAPAD
VLKLPAGRIGEGAPADLCVFDPNAHWRVEPRALKSQGHNTPFLGYELPARVCATLVAGQV
AFERR