MDB - MELIOIDOSIS DATABASE

  Protein search results for - A8KL35

Names and origin
Entry : A8KL35 (unreviewed)
Entry name : A8KL35_BURPE
Protein names : Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase)
Organism : Burkholderia pseudomallei Pasteur 52237
Organism ID : 331978
Gene names : purL
ORF names : BURPSPAST_AA1027
EC number : 6.3.5.3
History
Date of creation : 2007-12-04
Date of modification : 2014-09-03
Date of sequence modification : 2007-12-04
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' IMP biosynthetic process; ATP binding; cytoplasm; glutamine metabolic process; phosphoribosylformylglycinamidine synthase activity
GO identifier : GO:0006189; GO:0005524; GO:0005737; GO:0006541; GO:0004642
Keywords
Ligand & Biological process : ATP-binding; Cytoplasm; Glutamine amidotransferase; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis
General annotation
Domains : Glutamine amidotransferase type-1 domain (1)
Pathway : Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.
Sequence similarities : Belongs to FGAMS family
Subcellular location : Cytoplasm.
Protein sequence
Length : 1445 residues
>A8KL35|A8KL35_BURPE Burkholderia pseudomallei Pasteur 52237
MAHFSCFPGASALSDFRQTRLLDALKQIDGDIVAVRGQYLHFVNAHEPLTADDEARIGAL
MHYGAPLEPAAEKGATETFVVLPRFGTVSPWASKATDIARHCGLARVRRIERGIEFTVTL
KAGVLGVGAKKALAADARAAVAAALHDRMTESVVASREDARHLFDELPAKPLATVDVLAE
GRAALERANAELGLALADDEIDYLVDAFIKLERNPTDVELMMFAQANSEHCRHKIFNAQW
TIDGQAQDMSLFAMIRNTEEMSPQGTIVAYSDNSSIMSGAHAERWFPRGAGEPGERYGRH
TELTHTLMKVETHNHPSAISPFPGAATGAGGEIRDEGATGRGARPKAGLTGFTVSNLDLP
GARESWENARDAAQPAAARNAQQPCAPYGRPDRIASPLSIMIDGPLGGAAFNNEFGRPNL
GGYFRVYEQNVGGQVRGYHKPIMIAGGIGNISDAHTHKHDVPAGSLLIQIGGPGMRIGMG
GGAASSMATGANTAELDFDSVQRGNPEIERRAQEVINGCWQLGEHNPILSIHDVGAGGLS
NAFPEIVDGAGKGARFELRKIALEESGLSPREIWSNEAQERYVLAISPADLPRFEAICAR
ERCPFSVVGVATDERRLQLVDGEATGAAAYPVDMPMEVLLGKPPRMHRDVKRVHIERAGV
DVTGVALADAARDVLRHPTVASKSFLITIGDRTVGGTSVRDQMVGPWQVPVADCAVTALD
YAGFAGEAMTMAERTPLAVIDAPASGRMAVGEAITNIAAAPIASLDKLKLSANWMAACGT
EGEDAKLFDTVKAIGMELCPALGIGIPVGKDSLSMKTKWNDNGVAKEVVAPVSLIISAFA
PVEDVRRHLTPQLRRVADVGASVLIAIDLGRGKNRLGGSILAQVTQQVGDATPDVDDPED
LKRFFAAVQSLNARDLLLAYHDRSDGGLWATVCEMAFAGHAGVSLNVDMLTLDQQHESDY
GDAKDWAKQTSGRREDRTIRALFSEELGAVVQVRAADRDAVLGALREHGLSACSHVIGAV
NETDAIEVYRDAKKIYEAPRVELQRAWSEVSWRIARLRDNPACADAEYDAILDAGDPGLS
PVLTFDPAEDVAAPFIATGARPRVAILREQGVNSHLETAYAFDRAGFDAHDVHMSDLLAG
RATLADFAGAVACGGFSYGDVLGAGEGWAKTIRFNDKLADMFAAFFARPDTFALGICNGC
QMMSSLASMIPGAQAWPKFTRNKSEQFEARFSFVEVQSSPSIFFAGMEGSRIPVAVAHGE
GYADFSQQGDQSRVAVAMRYVDHRGDATERYPFNPNGSPAGITSVTTADGRFTVLMPHME
RVHRTVTMSWHPQGWGEASPWLRVFRNARRWIG