MDB - MELIOIDOSIS DATABASE

  Protein search results for - A8EAC1

Names and origin
Entry : A8EAC1 (unreviewed)
Entry name : A8EAC1_BURPE
Protein names : 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2)
Organism : Burkholderia pseudomallei 406e
Organism ID : 360118
Gene names : ispH
ORF names : BURPS406E_0339
EC number : 1.17.1.2
History
Date of creation : 2007-11-13
Date of modification : 2014-06-11
Date of sequence modification : 2007-11-13
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 3 iron, 4 sulfur cluster binding; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; dimethylallyl diphosphate biosynthetic process; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; metal ion binding; terpenoid biosynthetic process
GO identifier : GO:0051538; GO:0051745; GO:0050992; GO:0019288; GO:0046872; GO:0016114
Keywords
Ligand & Biological process : 3Fe-4S; Iron; Iron-sulfur; Isoprene biosynthesis; Metal-binding; NADP; Oxidoreductase
General annotation
Pathway : Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.
Sequence similarities : Belongs to IspH family
Protein sequence
Length : 337 residues
>A8EAC1|A8EAC1_BURPE Burkholderia pseudomallei 406e
MRVILAQPRGFCAGVVRAIEIVERALQQNGAPVYVRHEIVHNRHVVENLRNKGARFVEEL
DEVPHGAVAIFSAHGVAQTVEQDAQARGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIG
HAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPADTPVAYVTQTTLSVDDTRGIIEALQR
RFTDIVGPDTRDICYATQNRQAAVRELSEQVDVLLVVGATNSSNSNRLREIGTESGVPSY
LVADGSEVRAEWFANARTVGLTAGASAPEEMVEDVIAALRALGPLEVATMSGREEKVEFK
LPAKLTQAVAREV