MDB - MELIOIDOSIS DATABASE

  Protein search results for - A3N925

Names and origin
Entry : A3N925 (reviewed)
Entry name : PYRD_BURP6
Protein names : Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)
Organism : Burkholderia pseudomallei 668
Organism ID : 320373
Gene names : pyrD
ORF names : BURPS668_1809
EC number : 1.3.5.2
History
Date of creation : 2008-01-15
Date of modification : 2014-09-03
Date of sequence modification : 2007-04-03
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; dihydroorotate oxidase activity; plasma membrane
GO identifier : GO:0044205; GO:0006207; GO:0004158; GO:0005886
Keywords
Ligand & Biological process : Cell membrane; Complete proteome; FMN; Flavoprotein; Membrane; Oxidoreductase; Pyrimidine biosynthesis
General annotation
Pathway : Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.
Sequence similarities : Belongs to Dihydroorotate dehydrogenase family, Type 2 subfamily
Subcellular location : Cell membrane; Peripheral membrane protein.
Protein sequence
Length : 366 residues
>A3N925|PYRD_BURP6 Burkholderia pseudomallei 668
MFSSLYPLARASLFKMDAEDAHHLTLRMLGAAGRTGLACALSPRVPDAPRTVMGLSFRNP
VGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRLFRLPEADAIINRMGFNN
SGVDQFVKNVQAARYRGVLGLNIGKNADTPIERAADDYLYCLERVYPFASYVTINISSPN
TKNLRQLQGAGELDALLAALKDKQRRLADLHGKLVPLALKIAPDLDDEQVKEIAATLLRH
DIEGVIATNTTLSREAVKGLPHADEAGGLSGRPVFDASNAVIRKLRAELGDAVPIIGVGG
IFSGEDARAKLAAGAALVQLYTGFIYRGPALVAECVKAIARG