HIGDB: Haemophilus influenzae Genome Database

Protein search results for - P44514

Names and origin

Entry	:	P44514 (reviewed)
Entry name	:	DAPE_HAEIN
Protein names	:	Succinyl-diaminopimelate desuccinylase (SDAP desuccinylase) (EC 3.5.1.18) (N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase)
Organism	:	Haemophilus influenzae Rd KW20
Organism ID	:	71421
Gene names	:	dapE
ORF names	:	HI_0102
EC number	:	3.5.1.18

History

Date of creation	:	1995-11-01
Date of modification	:	2013-12-11
Date of sequence modification	:	1995-11-01

Protein attributes

Protein existence

Evidence at protein level

Gene Ontology (GO)

GO term name	:	cobalt ion binding; diaminopimelate biosynthetic process; lysine biosynthetic process via diaminopimelate; metallopeptidase activity; proteolysis; succinyl-diaminopimelate desuccinylase activity; zinc ion binding
GO identifier	:	GO:0050897; GO:0019877; GO:0009089; GO:0008237; GO:0006508; GO:0009014; GO:0008270

Keywords

Ligand & Biological process

3D-structure; Amino-acid biosynthesis; Cobalt; Complete proteome; Diaminopimelate biosynthesis; Direct protein sequencing; Hydrolase; Lysine biosynthesis; Metal-binding; Reference proteome; Zinc

General annotation

Pathway	:	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.
Sequence similarities	:	Belongs to Peptidase M20A family, DapE subfamily

Reference

PubMed ID

7542800; 9671518; 12962500; 14640610; 16421726; 18712420; 21577314; 20138056

Protein sequence

Length

405 residues

>P44514|DAPE_HAEIN Haemophilus influenzae Rd KW20
MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEP
VIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANP
NHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRG
SITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAG
TGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGK
LLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDL
GKCGEIYHKMLVNLLDS