HIGDB - Haemophilus influenzae Genome Database

Protein search results for - P44308

Names and origin
Entry : P44308 (reviewed)
Entry name : NADR_HAEIN
Protein names : Bifunctional NAD biosynthesis protein NadR [Includes: Nicotinamide mononucleotide adenylyltransferase (NMN adenylyltransferase) (NMN-AT) (NMNAT) (EC 2.7.7.1) (Nicotinamide ribonucleotide adenylyltransferase) (Nicotinamide-nucleotide adenylyltransferase);
Organism : Haemophilus influenzae Rd KW20
Organism ID : 71421
Gene names : nadR
ORF names : HI_0763
EC number : 2.7.7.1; 2.7.1.22
History
Date of creation : 1995-11-01
Date of modification : 2013-11-13
Date of sequence modification : 1995-11-01
Protein attributes
Protein existence : Evidence at protein level
Gene Ontology (GO)
GO term name : ATP binding; DNA binding; NAD biosynthetic process; cytoplasm; negative regulation of transcription, DNA-dependent; nicotinamide-nucleotide adenylyltransferase activity; plasma membrane; ribosylnicotinamide kinase activity; transport
GO identifier : GO:0005524; GO:0003677; GO:0009435; GO:0005737; GO:0045892; GO:0000309; GO:0005886; GO:0050262; GO:0006810
Keywords
Ligand & Biological process : 3D-structure; ATP-binding; Alternative initiation; Cell membrane; Complete proteome; Cytoplasm; Kinase; Membrane; Multifunctional enzyme; NAD; Nucleotide-binding; Pyridine nucleotide biosynthesis; Reference proteome; Transferase
General annotation
Pathway : Cofactor biosynthesis; NAD(+) biosynthesis [regulation]. Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
Sequence similarities : Belongs to Bacterial NMN adenylyltransferase family; Bacterial RNK family
Subcellular location : Cell membrane; Peripheral membrane protein. Cytoplasm.
Reference
PubMed ID : 7542800; 12446641; 15968050; 12068016
Protein sequence
Length : 453 residues
>P44308|NADR_HAEIN Haemophilus influenzae Rd KW20
MGFTTGREFHPALRMRAKYNAKYLGTKSEREKYFHLAYNKHTQFLRYQEQIMSKTKEKKV
GVIFGKFYPVHTGHINMIYEAFSKVDELHVIVCSDTVRDLKLFYDSKMKRMPTVQDRLRW
MQQIFKYQKNQIFIHHLVEDGIPSYPNGWQSWSEAVKTLFHEKHFEPSIVFSSEPQDKAP
YEKYLGLEVSLVDPDRTFFNVSATKIRTTPFQYWKFIPKEARPFFAKTVAILGGESSGKS
VLVNKLAAVFNTTSAWEYGREFVFEKLGGDEQAMQYSDYPQMALGHQRYIDYAVRHSHKI
AFIDTDFITTQAFCIQYEGKAHPFLDSMIKEYPFDVTILLKNNTEWVDDGLRSLGSQKQR
QQFQQLLKKLLDKYKVPYIEIESPSYLDRYNQVKAVIEKVLNEEEISELQNTTFPIKGTS
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