HIGDB - Haemophilus influenzae Genome Database

Protein search results for - P43777

Names and origin
Entry : P43777 (reviewed)
Entry name : HPPK_HAEIN
Protein names : 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK)
Organism : Haemophilus influenzae Rd KW20
Organism ID : 71421
Gene names : folK
ORF names : HI_0064
EC number : 2.7.6.3
History
Date of creation : 1995-11-01
Date of modification : 2013-11-13
Date of sequence modification : 1995-11-01
Protein attributes
Protein existence : Evidence at protein level
Gene Ontology (GO)
GO term name : 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; ATP binding; folic acid biosynthetic process; kinase activity; tetrahydrofolate biosynthetic process
GO identifier : GO:0003848; GO:0005524; GO:0046656; GO:0016301; GO:0046654
Keywords
Ligand & Biological process : 3D-structure; ATP-binding; Complete proteome; Folate biosynthesis; Kinase; Nucleotide-binding; Reference proteome; Transferase
General annotation
Pathway : Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.
Sequence similarities : Belongs to HPPK family
Reference
PubMed ID : 7542800; 10080886
Protein sequence
Length : 172 residues
>P43777|HPPK_HAEIN Haemophilus influenzae Rd KW20
MITAYIALGSNLNTPVEQLHAALKAISQLSNTHLVTTSSFYKSKPLGPQDQPDYVNAVAK
IETELSPLKLLDELQRIENEQGRVRLRRWGERTLDLDILLYGNEIIQNERLTIPHYDMHN
REFVIVPLFEIASDLVLPNSQIITELVKQFADHKMIKLNP