HIGDB - Haemophilus influenzae Genome Database

Protein search results for - Q4QMI7

Names and origin
Entry : Q4QMI7 (reviewed)
Entry name : FOLD_HAEI8
Protein names : Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
Organism : Haemophilus influenzae 86-028NP
Organism ID : 281310
Gene names : folD
ORF names : NTHI0864
EC number : 1.5.1.5; 3.5.4.9
History
Date of creation : 2006-12-12
Date of modification : 2013-11-13
Date of sequence modification : 2005-07-19
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : folic acid-containing compound biosynthetic process; histidine biosynthetic process; methenyltetrahydrofolate cyclohydrolase activity; methionine biosynthetic process; methylenetetrahydrofolate dehydrogenase (NADP+) activity; purine nucleotide biosyntheti
GO identifier : GO:0009396; GO:0000105; GO:0004477; GO:0009086; GO:0004488; GO:0006164; GO:0035999
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Hydrolase; Methionine biosynthesis; Multifunctional enzyme; NADP; One-carbon metabolism; Oxidoreductase; Purine biosynthesis
General annotation
Pathway : One-carbon metabolism; tetrahydrofolate interconversion.
Sequence similarities : Belongs to Tetrahydrofolate dehydrogenase/cyclohydrolase family
Reference
PubMed ID : 15968074
Protein sequence
Length : 302 residues
>Q4QMI7|FOLD_HAEI8 Haemophilus influenzae 86-028NP
MAAKIISGTELSKQIKANLADKITHYIEQGKRAPGLAVILVGADPASQIYVGNKRKSCEE
VGILSKSYDLPETTTQNELLAIIDQLNADKNIDGILVQLPLPKQINAEAIIERIDPKKDV
DGFHPYNVGRLCQRIPTLRACTPYGVMKLLETTGIDLHGKHAVIVGASNIVGRPMSLELL
LAGATVTVTHRFTKNLENHVRQADILVVAVGKPNLISGDWIKESAVVIDVGINRVDGKLV
GDVEFDKAAEKAAYITPVPGGVGPMTVAMLMSNTLYAYEHNK