HIGDB: Haemophilus influenzae Genome Database

Protein search results for - Q4QL43

Names and origin

Entry	:	Q4QL43 (reviewed)
Entry name	:	ISPE_HAEI8
Protein names	:	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase)
Organism	:	Haemophilus influenzae 86-028NP
Organism ID	:	281310
Gene names	:	ispE
ORF names	:	NTHI1434
EC number	:	2.7.1.148

History

Date of creation	:	2006-05-16
Date of modification	:	2013-11-13
Date of sequence modification	:	2006-05-16

Protein attributes

Protein existence

Inferred from homology

Gene Ontology (GO)

GO term name	:	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity; ATP binding; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; terpenoid biosynthetic process
GO identifier	:	GO:0050515; GO:0005524; GO:0019288; GO:0016114

Keywords

Ligand & Biological process

ATP-binding; Complete proteome; Isoprene biosynthesis; Kinase; Nucleotide-binding; Transferase

General annotation

Pathway	:	Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.
Sequence similarities	:	Belongs to GHMP kinase family, IspE subfamily

Reference

PubMed ID

15968074

Protein sequence

Length

337 residues

>Q4QL43|ISPE_HAEI8 Haemophilus influenzae 86-028NP
MKSHQFSTALCQNTTQSNGQPLRFPSPAKLNLFLYINGKLPNGYHELQTLFQFLDFGDWL
DISIREQDNQIVLTPEIPNLKTENNLIYRAAKLLQEKANIQLGANIHLDKILPMGGGVGG
GSSNAATALVSLNYLWQANLSIDELAKLGLTLGADVPIFVYGQAAFAEGVGEKITYCEPA
EKWFVILKPDDSISTAVIFQDPNLPRNTPKKSLEQLLSEPYKNDCEKVVINHYSNVEKAL
NWLLQYAPARLTGTGACVFAEFDHEAEAQAVFRQKPEAFFGFVAKGLNVSPLHAMLKQLS
STHTHRQSKPEVL