HIGDB - Haemophilus influenzae Genome Database

Protein search results for - P45345

Names and origin
Entry : P45345 (reviewed)
Entry name : PBPB_HAEIN
Protein names : Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpepti
Organism : Haemophilus influenzae Rd KW20
Organism ID : 71421
Gene names : mrcB
ORF names : ponB
EC number : 2.4.1.129; 3.4.-.-
History
Date of creation : 1995-11-01
Date of modification : 2013-11-13
Date of sequence modification : 1995-11-01
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : penicillin binding; peptidase activity; peptidoglycan biosynthetic process; peptidoglycan glycosyltransferase activity; peptidoglycan-based cell wall; plasma membrane; regulation of cell shape; response to antibiotic; transferase activity, transferring pe
GO identifier : GO:0008658; GO:0008233; GO:0009252; GO:0008955; GO:0009274; GO:0005886; GO:0008360; GO:0046677; GO:0016763
Keywords
Ligand & Biological process : Antibiotic resistance; Cell inner membrane; Cell membrane; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Glycosyltransferase; Hydrolase; Membrane; Multifunctional enzyme; Peptidoglycan synthesis; Reference proteome; Transferase
General annotation
Pathway : Cell wall biogenesis; peptidoglycan biosynthesis.
Sequence similarities : Belongs to Glycosyltransferase 51 family; Transpeptidase family
Subcellular location : Cell inner membrane.
Reference
PubMed ID : 7542800
Protein sequence
Length : 837 residues
>P45345|PBPB_HAEIN Haemophilus influenzae Rd KW20
MTSQHSAKKSSKNTPKNNRTFKGFLLKFSFTALVLTIFYGGYLDWQIRSKMDGQIWHLPA
EVYSRLESVKIADNLAFDEVIQILLDNEYRQTTMVAAPGDFKLEDDSIVVLRRAFPFPDK
AEPQRVLRLRFSHNKLSRIEDLVTVKTVDEFRLAPKLIAMLQSDNEDRLAIPLQNYPRLL
IDTLILTEDRRFYEHNGINPVGILRALIANIRAGQTVQGGSTLTQQLVKNLFLSRERTIT
RKANEALMSLVLDWRYDKNRILETYLNEIYLGQNGDTQIHGFELASQFYFGRSIREISLD
QIALLVGMVKGPSLYNPWRNPQNALERRNIVLRLMLEHKMIGDELYQLLSQRPLGVQKKG
QISRKYPAFIQTLQADLRRKLGEHKISSLLGARIFSTMDLKQQAQAENAVGNTVSQLQLK
MKNPHLEGAMIITDYRTGEIRAVVGGLQTQYAGFNRALMAKRQIGSLVKPSIYLTALSNP
EQFRLNTPINNQPITINVKGSPPWQPRNYDKKYSDSVMLMDALARSLNIPTVNIGMKVGL
SKVIDTQKAMGWDNVEIPKVPAMLLGSYTISPYDVTKLYQTLANQGGRIALTTVDSIADR
QGNLIFQHDKSAKQVVPQEAAFQTLFAMQQTVERGTARSLQKDYADLHLAGKTGTTNESR
DTWFVGIDGKNISTVWLGRDDNGETKLTGASGALQIYKDYLNRTNIEKLAITPPTTVKWV
GINQYGDWDCESYRTIPIWLNNGQNFCGETSSPSLTPTTETETPPQESLWDVLDNPNPPA
Q