HIGDB - Haemophilus influenzae Genome Database

Protein search results for - P44434

Names and origin
Entry : P44434 (reviewed)
Entry name : HIS2_HAEIN
Protein names : Histidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase (PRA-CH) (EC 3.5.4.19); Phosphoribosyl-ATP pyrophosphatase (PRA-PH) (EC 3.6.1.31)]
Organism : Haemophilus influenzae Rd KW20
Organism ID : 71421
Gene names : hisI
ORF names : hisIE
EC number : 3.5.4.19; 3.6.1.31
History
Date of creation : 1995-11-01
Date of modification : 2013-11-13
Date of sequence modification : 1995-11-01
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : ATP binding; cytoplasm; histidine biosynthetic process; phosphoribosyl-AMP cyclohydrolase activity; phosphoribosyl-ATP diphosphatase activity
GO identifier : GO:0005524; GO:0005737; GO:0000105; GO:0004635; GO:0004636
Keywords
Ligand & Biological process : ATP-binding; Amino-acid biosynthesis; Complete proteome; Cytoplasm; Histidine biosynthesis; Hydrolase; Multifunctional enzyme; Nucleotide-binding; Reference proteome
General annotation
Pathway : Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.
Sequence similarities : Belongs to PRA-CH family; PRA-PH family
Subcellular location : Cytoplasm.
Reference
PubMed ID : 7542800
Protein sequence
Length : 237 residues
>P44434|HIS2_HAEIN Haemophilus influenzae Rd KW20
MNITKIDWQKVNGLLPVIIQNISTREVLMLGYMNEEALTKTIKERKVTFFSRTKQRLWTK
GEISGNFLNVEEMSLDCDNDTLLILVDPIGATCHTGEYSCFHQFTSPQSENKKQQFANWA
WFIKLEQHLKEKKNADPSNSYTATLHAKGTKKIAQKVGEEGVETALAAVAQDKAEVISEA
TDLVYHLTVLLHNQDLQWYEIIAKLQERHQGIGLHPEGGNK