HIGDB - Haemophilus influenzae Genome Database

Protein search results for - P43791

Names and origin
Entry : P43791 (reviewed)
Entry name : DYR_HAEIN
Protein names : Dihydrofolate reductase (EC 1.5.1.3)
Organism : Haemophilus influenzae Rd KW20
Organism ID : 71421
Gene names : folA
ORF names : folH
EC number : 1.5.1.3
History
Date of creation : 1995-11-01
Date of modification : 2013-11-13
Date of sequence modification : 1995-11-01
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : NADP binding; dihydrofolate reductase activity; glycine biosynthetic process; nucleotide biosynthetic process; one-carbon metabolic process; response to antibiotic; tetrahydrofolate biosynthetic process
GO identifier : GO:0050661; GO:0004146; GO:0006545; GO:0009165; GO:0006730; GO:0046677; GO:0046654
Keywords
Ligand & Biological process : Antibiotic resistance; Complete proteome; NADP; One-carbon metabolism; Oxidoreductase; Reference proteome; Trimethoprim resistance
General annotation
Domains : DHFR (dihydrofolate reductase) domain (1)
Pathway : Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.
Sequence similarities : Belongs to Dihydrofolate reductase family
Reference
PubMed ID : 7542800;
Protein sequence
Length : 172 residues
>P43791|DYR_HAEIN Haemophilus influenzae Rd KW20
MTFSLIVATTLNNVIGKDNQMPWHLPADLAWFRQNTTGKPVIMGRKTFESIGRPLPKRTN
IVLSRQLFEHEGVIWKDSFESAVNFVRDFDEIMLIGGGELFKQYLPKADKLYLTQIQTEL
DGDTFFPQLNWEEWEIEFDEYRKADEQNRYDCRFLILTRK