HIGDB - Haemophilus influenzae Genome Database

Protein search results for - A5UD84

Names and origin
Entry : A5UD84 (unreviewed)
Entry name : A5UD84_HAEIE
Protein names : 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase)
Organism : Haemophilus influenzae PittEE
Organism ID : 374930
Gene names : leuB
ORF names : CGSHiEE_07030
EC number : 1.1.1.85
History
Date of creation : 2007-07-10
Date of modification : 2013-11-13
Date of sequence modification : 2007-07-10
Protein attributes
Protein existence : Inferred from homology
Gene Ontology (GO)
GO term name : 3-isopropylmalate dehydrogenase activity; NAD binding; cytoplasm; leucine biosynthetic process; magnesium ion binding
GO identifier : GO:0003862; GO:0051287; GO:0005737; GO:0009098; GO:0000287
Keywords
Ligand & Biological process : Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Cytoplasm; Leucine biosynthesis; Magnesium; Manganese; Metal-binding; NAD; Oxidoreductase
General annotation
Pathway : Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.
Sequence similarities : Belongs to Isocitrate and isopropylmalate dehydrogenases family, LeuB type 1 subfamily
Subcellular location : Cytoplasm.
Reference
PubMed ID : 17550610
Protein sequence
Length : 382 residues
>A5UD84|A5UD84_HAEIE Haemophilus influenzae PittEE
MQSYNIAVLAGDGIGPEVMAEAIKVLNRVQEKFGFKLNFNEFFVGGAAIDHCGCPLPAET
LKGCDEADAILFGSVGGPKWTNLPPDQQPERGALLPLRKHFKLFCNLRPATLYKGLEKFC
PLRADIAAKGFDMVVVRELTGGIYFGQPKGREGDGVQTKAFDTEVYYKYEIERIARAAFE
AAMKRNKKVTSVDKANVLQSSILWRETVTEMAKEYPEVTLEHIYIDNATMQLIKAPESFD
VLLCSNIFGDIISDEAAIITGSMGMLPSASLNEEGFGLYEPAGGSAPDIAGKGIANPITQ
ILSAAMMLRYSFNLNEAADAIESAVQKVLASGHRTADLADASTPVSTAEMGTLITQAI