EDB: Ebola Database

Protein search results for - Q91DE0

Names and origin

Entry	:	Q91DE0 (reviewed)
Entry name	:	VP35_EBORE
Protein names	:	Polymerase cofactor VP35
Organism	:	Reston ebolavirus (strain Philippines-96) (REBOV) (Reston Ebola virus)
Organism ID	:	129003
Gene names	:	VP35

History

Date of creation	:	2006-07-11
Date of modification	:	2014-10-29
Date of sequence modification	:	2001-12-01

Protein attributes

Protein existence

Inferred from homology

Gene Ontology (GO)

GO term name	:	host cell cytoplasm; RNA binding; suppression by virus of host IKBKE activity; suppression by virus of host IRF7 activity; suppression by virus of host TBK1 activity; suppression by virus of host toll-like receptor signaling pathway; transcription, DNA-templated; virion
GO identifier	:	GO:0003723; GO:0030430; GO:0039724; GO:0039557; GO:0039723; GO:0039722; GO:0006351; GO:0019012

Keywords

Ligand & Biological process

Coiled coil; Complete proteome; Host cytoplasm; Host-virus interaction; Inhibition of host IKBKE by virus; Inhibition of host IRF7 by virus; Inhibition of host RLR pathway by virus; Inhibition of host TBK1 by virus; Inhibition of host TLR pathway by virus; Inhibition of host innate immune response by virus; Interferon antiviral system evasion; RNA-binding; Transcription; Viral RNA replication; Viral immunoevasion; Virion

General annotation

Sequence similarities	:	Belongs to Filoviridae polymerase cofactor VP35 family
Subcellular location	:	Virion. Host cytoplasm {ECO:0000250}.

Reference

PubMed ID

11722021

Protein sequence

Length

353 residues

>Q91DE0|VP35_EBORE Reston ebolavirus (strain Philippines-96) (REBOV) (Reston Ebola virus)
MYNDKLKICSGPETTGWISEQLMTGKIPVTDIFIDIDNKPDQMEVRLKPSSRSSTRTCTS
SSQTEVNYVPLLKKVEDTLTMLVSATSRQNAAIEALENRLSTLESSLKPIQDMGKVISSL
NRSCAEMVAKYDLLVMTTGRATSTAAAVDAYWKEHKQPPPGPALYEENALKGKIDDPNSY
VPDAVQEAYKNLDSTSTLTEENFGKPYISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGK
DNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPTIHIRSRGDIPRACQKSL
RPAPPSPKIDRGWVCLFKMQDGKTLGLKI